Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710055 | 0.94 | IRAK4 (0.41) | IRAK4GRM5RXFP1PDE10ANR1H4 | |
| SCHEMBL6711406 | 0.93 | GRIK1 (0.38) | GRIK1RXFP1NR1H4TDP1GPR35 | |
| SCHEMBL6710389 | 0.91 | MEN1 (0.40) | IRAK4GRIK1GRM5RXFP1BRAF | |
| SCHEMBL6713760 | 0.90 | GRIK1 (0.42) | GRIK1RXFP1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6708679 | 0.90 | GRIK1 (0.44) | GRIK1RXFP1TDP1HIF1ANPSR1 | |
| SCHEMBL6708854 | 0.89 | KMT2A (0.42) | IRAK4RXFP1PDE10ANR1H4HDAC1 | |
| SCHEMBL6712044 | 0.88 | GPR35 (0.46) | GRIK1RXFP1GPR35 | |
| SCHEMBL6709159 | 0.87 | TP53 (0.39) | IRAK4GRM5RXFP1GPR35HDAC1 | |
| SCHEMBL6713931 | 0.86 | GRIK1 (0.41) | GRIK1RXFP1NR1H4TDP1HIF1A | |
| SCHEMBL6711934 | 0.85 | PRSS12 (0.39) | RXFP1NR1H4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | IRAK4 1592/4885GRIK1 3885/4885GRM5 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.