Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710489 | 0.84 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL6710517 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1ALOX15KDM4E | |
| SCHEMBL6707565 | 0.79 | — | — | |
| SCHEMBL6712341 | 0.77 | DDB1 (0.38) | ALDH1A1CYP3A4HTT | |
| SCHEMBL6708901 | 0.76 | — | — | |
| SCHEMBL6708886 | 0.75 | PYGL (0.32) | — | |
| SCHEMBL6707666 | 0.73 | RAD52 (0.38) | ALDH1A1CYP3A4THRBALOX15KDM4E | |
| SCHEMBL5390131 | 0.73 | PRKCQ (0.43) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL5382559 | 0.72 | PRKCQ (0.42) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL21460310 | 0.71 | LMNA (0.44) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | claimed |
| EP-1341510-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2003-09-10 | — | — | EP | claimed |
| WO-2002045671-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-06-13 | — | — | WO | claimed |
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | disclosed |
| EP-1341510-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045671-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | KRT18, PYCR1, COX5A | ALDH1A1 203/4885CYP3A4 244/4885TDP1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.