Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 3/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707755 | 0.95 | PARP14 (0.43) | PTK2BPARP14KDRKDM4EMEN1 | |
| SCHEMBL6709118 | 0.93 | PTK2B (0.40) | PTK2BPARP14RAB9ANPC1P2RY14 | |
| SCHEMBL6708820 | 0.93 | PARP14 (0.41) | PARP14MAPK1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6710593 | 0.92 | PARP14 (0.38) | PTK2BPARP14MAPTMAPK1MEN1 | |
| SCHEMBL6707704 | 0.92 | PTK2B (0.39) | PTK2BPARP14MEN1KMT2APLCG2 | |
| SCHEMBL6708944 | 0.92 | PARP14 (0.39) | PARP14MAPTMEN1TP53KMT2A | |
| SCHEMBL6708914 | 0.92 | MEN1 (0.47) | PARP14KDRMAPTP2RY14KDM4E | |
| SCHEMBL6713211 | 0.91 | PARP14 (0.42) | PARP14KDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL6712041 | 0.91 | LMNA (0.41) | PTK2BPARP14MEN1ALDH1A1KMT2A | |
| SCHEMBL6708687 | 0.91 | P2RY14 (0.40) | PARP14MAPTP2RY14TP53PLCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PTK2B 4069/4885PARP14 2597/4885KDR 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.