Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 4/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707755 | 0.94 | PARP14 (0.43) | PARP14PYGLTP53PLCG2PTK2B | |
| SCHEMBL6709152 | 0.92 | PTK2B (0.42) | PARP14MAPTTP53PLCG2MAPK1 | |
| SCHEMBL6713381 | 0.92 | NLRP3 (0.36) | PARP14NLRP3MAP3K5MAPTTP53 | |
| SCHEMBL6708820 | 0.91 | PARP14 (0.41) | PARP14TP53PLCG2MAPK1NHERF1 | |
| SCHEMBL6707704 | 0.91 | PTK2B (0.39) | PARP14NLRP3PLCG2PTK2BF10 | |
| SCHEMBL6708944 | 0.91 | PARP14 (0.39) | PARP14MAPTTP53PLCG2NHERF1 | |
| SCHEMBL6714087 | 0.91 | NPY5R (0.42) | PARP14NLRP3PLCG2NHERF1LMNA | |
| SCHEMBL6708914 | 0.90 | MEN1 (0.47) | PARP14MAPTTP53LMNAPOLB | |
| SCHEMBL6713211 | 0.90 | PARP14 (0.42) | PARP14TP53F10NHERF1POLB | |
| SCHEMBL6712041 | 0.90 | LMNA (0.41) | PARP14PLCG2PTK2BNHERF1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885NLRP3 280/4885PYGL 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.