Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 9/20 | 0.34 |
| ▸ | EIF4E | P06730 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711764 | 0.91 | GCK (0.33) | SCN2ASCN10ATRPA1LMNAMAPT | |
| SCHEMBL6707800 | 0.88 | NPSR1 (0.37) | BRPF1RXFP1BRD4KDM4ELMNA | |
| SCHEMBL6709856 | 0.88 | RXFP1 (0.38) | BRPF1RXFP1JAK2JAK1TYK2 | |
| SCHEMBL6707714 | 0.88 | NR2E1 (0.35) | TRPA1RXFP1ROCK2LMNAMAPT | |
| SCHEMBL6708936 | 0.88 | KDM1A (0.34) | BRPF1RXFP1BRD4LMNAMAPT | |
| SCHEMBL6710104 | 0.87 | TRPA1 (0.33) | TRPA1ROCK2LMNA | |
| SCHEMBL6712448 | 0.87 | KDM4E (0.36) | KDM4ELMNAMAPT | |
| SCHEMBL6710191 | 0.86 | ALK (0.38) | IRAK4TRPA1RXFP1JAK2JAK1 | |
| SCHEMBL6710200 | 0.86 | ALK (0.38) | IRAK4TRPA1RXFP1JAK2JAK1 | |
| SCHEMBL6709131 | 0.86 | PPIA (0.39) | RXFP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | SCN2A 2643/4885SCN10A 2961/4885IRAK4 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.