Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713833 | 0.90 | CXCR1 (0.34) | TRPA1PKMROCK2CXCR1CXCR2 | |
| SCHEMBL6710210 | 0.89 | GSK3A (0.36) | TRPA1THRBGRM5KMT2A | |
| SCHEMBL6709087 | 0.88 | TRPA1 (0.42) | TRPA1ROCK2LMNAGRM4KMT2A | |
| SCHEMBL6708989 | 0.88 | LMNA (0.38) | TRPA1PKMROCK2LMNAGRM4 | |
| SCHEMBL6711902 | 0.88 | THRB (0.37) | TRPA1PKMLMNAGRM4THRB | |
| SCHEMBL6709167 | 0.87 | SCN2A (0.36) | TRPA1ROCK2LMNA | |
| SCHEMBL6708677 | 0.87 | PKM (0.34) | TRPA1PKMROCK2LMNATHRB | |
| SCHEMBL6713815 | 0.86 | HIF1A (0.41) | LMNAGRM4KMT2A | |
| SCHEMBL6708796 | 0.86 | RXFP1 (0.39) | LMNAGRM4KMT2A | |
| SCHEMBL6711975 | 0.86 | TRPA1 (0.46) | TRPA1ROCK2LMNAGRM4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | TRPA1 594/4885PKM 3958/4885ROCK2 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.