SCHEMBL6709353

SCHEMBL6709353

CC(C)(F)C(=O)N(F)F.O=S(=O)(c1ccccc1)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.40
APOBEC3G Q9HC16 1/20 0.39
KIF11 P52732 2/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
ABCC9 O60706 1/20 0.38
ABCC8 Q09428 1/20 0.38
KCNJ11 Q14654 1/20 0.38
KCNJ8 Q15842 1/20 0.38
NR1H3 Q13133 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 1/20 0.37
RECQL P46063 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777153 0.78 HTR6 (0.50) HSD11B1APOBEC3GKIF11TSHRALDH1A1
SCHEMBL28144575 0.72 HSD11B1 (0.46) HSD11B1KMT2AMEN1ABCC9ABCC8
SCHEMBL6053237 0.70 HSD11B1 (0.47) HSD11B1APOBEC3GKMT2AMEN1ABCC9
SCHEMBL1018442 0.70 CA1 (0.55) KIF11KMT2ATSHRCYP2C19ALDH1A1
SCHEMBL28469203 0.69 ALDH1A1 (0.46) HSD11B1APOBEC3GKMT2AMEN1ABCC9
SCHEMBL19033894 0.68 HTR6 (0.48) HSD11B1APOBEC3GTSHRCYP2C19NPSR1
SCHEMBL9052913 0.68 KMT2A (0.44) KMT2AMEN1NR1H3CYP1A2CYP3A4
SCHEMBL1464395 0.67 HSD11B1 (0.48) HSD11B1KMT2ATSHRCYP2C19ALDH1A1
SCHEMBL28217808 0.67 KIF11 (0.58) KIF11KMT2AMEN1ALDH1A1RECQL
SCHEMBL10652867 0.67 TSHR (0.48) HSD11B1KMT2AMEN1ABCC9ABCC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6829257-B2 Transverse flowing liquid Kerr cell for high average power laser Q-switching and for direct modulation of high power laser beams. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-12-07 US claimed
US-20040146074-A1 Transverse flowing liquid Kerr Cell for high average power laser Q-switching and for direct modulation of high power laser beams THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-07-29 US claimed
US-6829257-B2 Transverse flowing liquid Kerr cell for high average power laser Q-switching and for direct modulation of high power laser beams. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-12-07 US disclosed
US-20040146074-A1 Transverse flowing liquid Kerr Cell for high average power laser Q-switching and for direct modulation of high power laser beams THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-07-29 US disclosed