Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 8/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711796 | 0.91 | HIF1A (0.36) | ROCK1F10RXFP1CCR9F2 | |
| SCHEMBL6710144 | 0.90 | ROCK1 (0.39) | ROCK1F10RXFP1GRM4 | |
| SCHEMBL6710384 | 0.88 | F10 (0.33) | ROCK1F10F2PRSS1PRSS2 | |
| SCHEMBL6711650 | 0.88 | SERPINE1 (0.38) | ROCK1F10RXFP1GRM4 | |
| SCHEMBL6712077 | 0.84 | GRIK1 (0.39) | ROCK1F10RXFP1AVPR2GPR27 | |
| SCHEMBL6709968 | 0.84 | LMNA (0.39) | ROCK1RXFP1GRM4 | |
| SCHEMBL6708796 | 0.84 | RXFP1 (0.39) | ROCK1RXFP1GRM4 | |
| SCHEMBL6711863 | 0.84 | GRM4 (0.37) | ROCK1F10RXFP1HSD11B1GRM4 | |
| SCHEMBL6712526 | 0.83 | RXFP1 (0.39) | ROCK1F10RXFP1GRM4 | |
| SCHEMBL6711949 | 0.83 | GRM4 (0.36) | ROCK1F10RXFP1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK1 4830/4885F10 2246/4885PTGS2 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.