Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914316 | 0.93 | CNR1 (0.34) | SERPINE1ROCK1NR1H4PPARGCNR1 | |
| SCHEMBL6710144 | 0.91 | ROCK1 (0.39) | SERPINE1ROCK1RXFP1GRM4KDM4E | |
| SCHEMBL6707725 | 0.90 | HIF1A (0.38) | ROCK1NR1H4RXFP1TP53KDM4E | |
| SCHEMBL6710331 | 0.88 | NR1H4 (0.38) | ROCK1NR1H4TP53KDM4EALDH1A1 | |
| SCHEMBL6709776 | 0.88 | ROCK1 (0.36) | ROCK1RXFP1GRM4F10 | |
| SCHEMBL6709968 | 0.85 | LMNA (0.39) | ROCK1CNR1RXFP1TP53GRM4 | |
| SCHEMBL6708796 | 0.85 | RXFP1 (0.39) | ROCK1RXFP1GRM4KDM4EMAPT | |
| SCHEMBL6711863 | 0.84 | GRM4 (0.37) | ROCK1RXFP1TP53GRM4MAPT | |
| SCHEMBL6714161 | 0.84 | GRIK1 (0.40) | SERPINE1ROCK1NR1H4PPARGCNR1 | |
| SCHEMBL6712526 | 0.84 | RXFP1 (0.39) | ROCK1RXFP1TP53GRM4F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | SERPINE1 2108/4885ROCK1 4830/4885NR1H4 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.