Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711396 | 0.90 | HSD11B1 (0.38) | RXFP1HSD11B1 | |
| SCHEMBL6712008 | 0.89 | HIF1A (0.40) | HIF1ANPSR1RXFP1GPR35KMT2A | |
| SCHEMBL6710507 | 0.88 | HIF1A (0.42) | HIF1ANPSR1RXFP1GPR35KMT2A | |
| SCHEMBL6707965 | 0.88 | NTRK1 (0.35) | RXFP1KMT2AHSD11B1NTRK1 | |
| SCHEMBL6710170 | 0.88 | NPSR1 (0.43) | HIF1ANPSR1RXFP1GPR35KMT2A | |
| SCHEMBL6711744 | 0.86 | GPR35 (0.42) | HIF1ANPSR1RXFP1GPR35KMT2A | |
| SCHEMBL6711759 | 0.86 | HIF1A (0.37) | HIF1ANPSR1RXFP1GPR35PTGFR | |
| SCHEMBL6708968 | 0.85 | HIF1A (0.41) | HIF1ANPSR1RXFP1GPR35KMT2A | |
| SCHEMBL6713815 | 0.85 | HIF1A (0.41) | HIF1ANPSR1RXFP1GPR35KMT2A | |
| SCHEMBL6710074 | 0.84 | GRIK1 (0.38) | HIF1ANPSR1RXFP1GPR35KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885NPSR1 2999/4885RXFP1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.