Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.39 |
| ▸ | PTGFR | P43088 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CCKAR | P32238 | 3/20 | 0.34 |
| ▸ | CCKBR | P32239 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710507 | 0.91 | HIF1A (0.42) | HIF1ANPSR1RXFP1KMT2AGPR35 | |
| SCHEMBL6711863 | 0.90 | GRM4 (0.37) | RXFP1KMT2ALMNACCKARCCKBR | |
| SCHEMBL6710170 | 0.90 | NPSR1 (0.43) | HIF1ANPSR1RXFP1KMT2AGPR35 | |
| SCHEMBL6709863 | 0.89 | HIF1A (0.38) | HIF1ANPSR1RXFP1KMT2AGPR35 | |
| SCHEMBL6711744 | 0.88 | GPR35 (0.42) | HIF1ANPSR1RXFP1KMT2AGPR35 | |
| SCHEMBL6711902 | 0.88 | THRB (0.37) | KMT2ALMNACCKARCCKBRF10 | |
| SCHEMBL6708968 | 0.88 | HIF1A (0.41) | HIF1ANPSR1RXFP1KMT2AGPR35 | |
| SCHEMBL6713815 | 0.87 | HIF1A (0.41) | HIF1ANPSR1RXFP1KMT2AGPR35 | |
| SCHEMBL6710547 | 0.85 | GRM4 (0.41) | HIF1ANPSR1RXFP1KMT2ALMNA | |
| SCHEMBL6710150 | 0.85 | RXFP1 (0.39) | HIF1ANPSR1RXFP1KMT2AGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885NPSR1 2999/4885RXFP1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.