Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 3/20 | 0.39 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713646 | 0.91 | NHERF1 (0.40) | ALDH1A1ADRB2CCKARCCKBRHTT | |
| SCHEMBL6707634 | 0.89 | CCKAR (0.38) | ALDH1A1ADRB2CCKARCCKBRHTT | |
| SCHEMBL6710377 | 0.88 | MMP2 (0.42) | ALDH1A1GRIK1KDM4E | |
| SCHEMBL6710011 | 0.87 | NPC1 (0.45) | GRIK1 | |
| SCHEMBL6711794 | 0.87 | ALDH1A1 (0.46) | ALDH1A1HTTGRIK1LMNAMAPT | |
| SCHEMBL6710051 | 0.87 | MEN1 (0.40) | ALDH1A1GRIK1KDM4E | |
| SCHEMBL6708867 | 0.86 | GRIK1 (0.40) | HTTGRIK1LMNA | |
| SCHEMBL6710295 | 0.86 | NPC1 (0.42) | GRIK1 | |
| SCHEMBL6713760 | 0.86 | GRIK1 (0.42) | GRIK1MAPTRXFP1 | |
| SCHEMBL6714337 | 0.85 | CCKAR (0.40) | ALDH1A1ADRB2CCKARCCKBRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ALDH1A1 123/4885ADRB2 3735/4885CCKAR 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.