Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.33 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707685 | 0.92 | GRIK1 (0.42) | GRIK1PLCG2PLA2G7POLBPTK2B | |
| SCHEMBL6714070 | 0.91 | GRIK1 (0.37) | GRIK1POLBHDAC1HDAC2MAPK10 | |
| SCHEMBL6711491 | 0.91 | GRIK1 (0.41) | GRIK1PLCG2PLA2G7POLBPTK2B | |
| SCHEMBL6708935 | 0.91 | GRIK1 (0.41) | GRIK1PLCG2PLA2G7MDM2PYGL | |
| SCHEMBL6708773 | 0.90 | GRIK1 (0.41) | GRIK1PLCG2SERPINE1PLA2G7MDM2 | |
| SCHEMBL6708822 | 0.89 | RORC (0.34) | PLA2G7HDAC1HDAC2MAPK10PIP5K1C | |
| SCHEMBL6707660 | 0.86 | PLCG2 (0.37) | PLCG2SERPINE1POLBPYGLPTK2B | |
| SCHEMBL6707970 | 0.85 | GRIK1 (0.39) | GRIK1PLCG2PLA2G7POLBPYGL | |
| SCHEMBL6707972 | 0.85 | GRIK1 (0.39) | GRIK1PLCG2PLA2G7POLBPYGL | |
| SCHEMBL6707967 | 0.85 | GRIK1 (0.39) | GRIK1PLCG2PLA2G7POLBPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885PLCG2 4289/4885SERPINE1 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.