Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | PIP5K1C | O60331 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.31 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713911 | 0.92 | GRIK1 (0.40) | GRIK1NSD2MAPTGPR35TP53 | |
| SCHEMBL6710073 | 0.91 | GRIK1 (0.39) | GRIK1PIP5K1CPIK3CAHDAC1HDAC2 | |
| SCHEMBL6707746 | 0.91 | GRIK1 (0.39) | GRIK1NSD2MAPTGPR35POLB | |
| SCHEMBL6709354 | 0.91 | GPR35 (0.40) | GRIK1NSD2MAPTGPR35POLB | |
| SCHEMBL6712074 | 0.90 | GPR35 (0.41) | GRIK1MAPTGPR35POLBRXFP1 | |
| SCHEMBL6708822 | 0.89 | RORC (0.34) | PIP5K1CPIK3CAHDAC3HDAC1HDAC2 | |
| SCHEMBL6709868 | 0.86 | GPR35 (0.35) | PIP5K1CPIK3CAHDAC3HDAC1HDAC2 | |
| SCHEMBL6708679 | 0.85 | GRIK1 (0.44) | GRIK1NSD2MAPTGPR35TP53 | |
| SCHEMBL6709003 | 0.85 | GRIK1 (0.37) | GRIK1HDAC3HDAC1HDAC2NSD2 | |
| SCHEMBL6709006 | 0.85 | GRIK1 (0.37) | GRIK1HDAC3HDAC1HDAC2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885PIP5K1C 2879/4885PIK3CA 2906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.