Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 2/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708060 | 0.91 | KMT2A (0.39) | PLCG2POLBPYGLPTK2BNHERF1 | |
| SCHEMBL6709868 | 0.91 | GPR35 (0.35) | POLBMAPK10ULK1HDAC1HDAC2 | |
| SCHEMBL6713856 | 0.90 | PLCG2 (0.38) | PLCG2PYGLPTK2BNHERF1KMT2A | |
| SCHEMBL6710117 | 0.89 | GRM5 (0.39) | PLCG2SERPINE1PYGLPTK2BNHERF1 | |
| SCHEMBL6708999 | 0.89 | RORC (0.34) | MAPK10ULK1HDAC1HDAC2PIP5K1C | |
| SCHEMBL6710073 | 0.86 | GRIK1 (0.39) | PLCG2SERPINE1POLBMAPK10ULK1 | |
| SCHEMBL6919649 | 0.85 | HDAC1 (0.37) | PLCG2HDAC1HDAC2PYGLPTK2B | |
| SCHEMBL6711711 | 0.84 | ROCK2 (0.36) | PLCG2ULK1HDAC1HDAC2PYGL | |
| SCHEMBL6711704 | 0.84 | ROCK2 (0.36) | PLCG2ULK1HDAC1HDAC2PYGL | |
| SCHEMBL6711709 | 0.84 | ROCK2 (0.36) | PLCG2ULK1HDAC1HDAC2PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PLCG2 4289/4885SERPINE1 2108/4885POLB 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.