Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713287 | 0.89 | AAK1 (0.42) | KMT2ANAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6711770 | 0.88 | GSK3B (0.37) | KMT2ANPC1RAB9ASMN1; SMN2PARP14 | |
| SCHEMBL6711579 | 0.88 | CHRM1 (0.41) | NAMPTNPC1RAB9ASMN1; SMN2P2RX7 | |
| SCHEMBL6713895 | 0.88 | GSK3B (0.37) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6711962 | 0.88 | ALDH1A1 (0.35) | KMT2ANPC1RAB9ASMN1; SMN2DRD2 | |
| SCHEMBL6709018 | 0.87 | PKM (0.35) | PARP14 | |
| SCHEMBL6709998 | 0.87 | GSK3B (0.37) | KMT2ANPC1RAB9ASMN1; SMN2PARP14 | |
| SCHEMBL6709971 | 0.87 | GSK3B (0.40) | PARP14DRD2DRD3 | |
| SCHEMBL6711789 | 0.86 | PARP14 (0.36) | NAMPTPARP14 | |
| SCHEMBL6711369 | 0.86 | KMT2A (0.42) | KMT2ATSHRNAMPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | KMT2A 3181/4885TSHR 3901/4885NAMPT 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.