Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713877 | 0.89 | TRPA1 (0.43) | TRPA1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6710552 | 0.89 | KMT2A (0.41) | ALDH1A1KMT2AMEN1NSD2FTO | |
| SCHEMBL6708511 | 0.89 | MEN1 (0.41) | ALDH1A1KMT2AMEN1POLBNSD2 | |
| SCHEMBL6711934 | 0.88 | PRSS12 (0.39) | KMT2AMEN1NSD2PLA2G7 | |
| SCHEMBL6708854 | 0.87 | KMT2A (0.42) | ALDH1A1KMT2AMEN1NSD2PLA2G7 | |
| SCHEMBL6830653 | 0.86 | TRPA1 (0.47) | TRPA1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6709960 | 0.86 | CHRNB2 (0.41) | NSD2 | |
| SCHEMBL6711762 | 0.85 | MAP3K5 (0.41) | ALDH1A1KMT2APOLBNSD2PLA2G7 | |
| SCHEMBL6707774 | 0.85 | TDP1 (0.44) | ALDH1A1KMT2AMEN1GSK3AGSK3B | |
| SCHEMBL6713406 | 0.85 | NPC1 (0.41) | PLA2G7LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | TRPA1 594/4885ALDH1A1 123/4885KMT2A 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.