Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713616 | 0.90 | CCKAR (0.37) | ROCK2TRPA1ROCK1LCKGRM4 | |
| SCHEMBL6707644 | 0.89 | LMNA (0.38) | ROCK2TRPA1ROCK1LCKGRM4 | |
| SCHEMBL6710337 | 0.89 | ROCK1 (0.41) | ROCK2TRPA1ROCK1HSD11B1LCK | |
| SCHEMBL6711759 | 0.89 | HIF1A (0.37) | TRPA1ROCK1HSD11B1LCKGRM4 | |
| SCHEMBL6707965 | 0.86 | NTRK1 (0.35) | TRPA1NTRK1HSD11B1WDR5SLC22A12 | |
| SCHEMBL6713525 | 0.85 | ROCK1 (0.36) | TRPA1ROCK1NTRK1WDR5LCK | |
| SCHEMBL6711975 | 0.85 | TRPA1 (0.46) | ROCK2TRPA1ROCK1LCKGRM4 | |
| SCHEMBL6835629 | 0.83 | ALB (0.39) | TRPA1ROCK1NTRK1WDR5AR | |
| SCHEMBL6707942 | 0.81 | LCK (0.37) | ROCK2LCK | |
| SCHEMBL6708021 | 0.81 | MAPT (0.41) | ROCK2TRPA1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK2 4868/4885TRPA1 594/4885ROCK1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.