Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713276 | 0.94 | HIF1A (0.43) | HIF1AALDH1A1ERBB2HSP90AA1HSP90AB1 | |
| SCHEMBL6710218 | 0.93 | HIF1A (0.43) | HIF1AMEN1KMT2AGPR27AVPR2 | |
| SCHEMBL6710201 | 0.92 | TDP1 (0.39) | HIF1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6708030 | 0.91 | ALDH1A1 (0.39) | HIF1AALDH1A1HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL6713466 | 0.89 | GPR27 (0.39) | HIF1AALDH1A1MEN1KMT2AGPR27 | |
| SCHEMBL6707764 | 0.88 | HIF1A (0.41) | HIF1AMEN1KMT2APOLBCLK1 | |
| SCHEMBL6710314 | 0.88 | HIF1A (0.41) | HIF1AALDH1A1PTPN2PTPN1PTPN5 | |
| SCHEMBL6710162 | 0.87 | HIF1A (0.48) | HIF1AMAPT | |
| SCHEMBL6710483 | 0.86 | HIF1A (0.46) | HIF1AALDH1A1ERBB2HSP90AA1HSP90AB1 | |
| SCHEMBL6709048 | 0.86 | KMT2A (0.38) | HIF1AALDH1A1MEN1KMT2AGPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885ALDH1A1 123/4885ERBB2 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.