Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 10/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710186 | 0.93 | HIF1A (0.43) | HIF1AGPR27AVPR2MEN1KMT2A | |
| SCHEMBL6713461 | 0.91 | GPR27 (0.39) | HIF1AGPR27AVPR2MEN1KMT2A | |
| SCHEMBL6709230 | 0.88 | GPR27 (0.41) | HIF1AGPR27AVPR2MEN1KMT2A | |
| SCHEMBL6710201 | 0.88 | TDP1 (0.39) | HIF1AMEN1KMT2AHTTTP53 | |
| SCHEMBL6713276 | 0.88 | HIF1A (0.43) | HIF1AGPR27AVPR2MEN1KMT2A | |
| SCHEMBL6708781 | 0.86 | HIF1A (0.45) | HIF1AGPR27AVPR2MEN1KMT2A | |
| SCHEMBL6710157 | 0.85 | ALDH1A1 (0.40) | HIF1AMEN1KMT2AHTTCYP2C19 | |
| SCHEMBL6710314 | 0.84 | HIF1A (0.41) | HIF1A | |
| SCHEMBL6710162 | 0.84 | HIF1A (0.48) | HIF1A | |
| SCHEMBL6707764 | 0.84 | HIF1A (0.41) | HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885GPR27 1616/4885AVPR2 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.