Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707741 | 0.98 | HDAC1 (0.40) | ADORA3MAOBADORA1MEN1KMT2A | |
| SCHEMBL6708940 | 0.95 | ALOX15 (0.44) | MEN1KMT2AGRIK1ALOX15MAPK1 | |
| SCHEMBL6710256 | 0.91 | RAB9A (0.41) | MEN1KMT2AGRIK1HDAC3HDAC1 | |
| SCHEMBL6710011 | 0.91 | NPC1 (0.45) | MEN1KMT2AGRIK1HDAC3HDAC1 | |
| SCHEMBL6709861 | 0.91 | GRIK1 (0.41) | MEN1KMT2AGRIK1MAPK1PLCG2 | |
| SCHEMBL6710607 | 0.90 | GRIK1 (0.41) | GRIK1ALOX15HDAC3HDAC1PLCG2 | |
| SCHEMBL6713462 | 0.90 | HDAC3 (0.41) | GRIK1ALOX15HDAC3HDAC1PLCG2 | |
| SCHEMBL6710059 | 0.89 | HDAC3 (0.42) | GRIK1ALOX15HDAC3HDAC1PLCG2 | |
| SCHEMBL6756845 | 0.89 | HDAC3 (0.42) | GRIK1ALOX15HDAC3HDAC1PLCG2 | |
| SCHEMBL6707622 | 0.89 | HDAC1 (0.37) | MEN1KMT2AHDAC3HDAC1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ADORA3 3118/4885MAOB 1290/4885ADORA1 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.