Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710296 | 0.95 | ADORA3 (0.41) | ALOX15MAPK1GRIK1HDAC3HDAC1 | |
| SCHEMBL6707741 | 0.95 | HDAC1 (0.40) | ALOX15MAPK1GRIK1HDAC3HDAC1 | |
| SCHEMBL6709861 | 0.92 | GRIK1 (0.41) | MAPK1GRIK1SMN1; SMN2PLCG2MEN1 | |
| SCHEMBL6710377 | 0.91 | MMP2 (0.42) | GRIK1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6712433 | 0.90 | GRIK1 (0.42) | MAPK1GRIK1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL6708770 | 0.89 | GRIK1 (0.41) | GRIK1HDAC1PLCG2MEN1KMT2A | |
| SCHEMBL6707994 | 0.88 | CETP (0.43) | GRIK1PLCG2NHERF1 | |
| SCHEMBL6713646 | 0.88 | NHERF1 (0.40) | GRIK1SMN1; SMN2PLCG2NHERF1KDM4E | |
| SCHEMBL6711734 | 0.88 | PARP14 (0.37) | HDAC3HDAC1HDAC2NCOR2PLCG2 | |
| SCHEMBL6710141 | 0.88 | GRIK1 (0.44) | GRIK1PLCG2NHERF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ALOX15 857/4885MAPK1 2728/4885GRIK1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.