Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.38 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711546 | 0.95 | GALR3 (0.37) | GALR3NR2F2NHERF1PLCG2PARP14 | |
| SCHEMBL6708676 | 0.94 | PARP14 (0.43) | GALR3NR2F2NHERF1PLCG2PARP14 | |
| SCHEMBL6707786 | 0.93 | GALR3 (0.36) | GALR3NR2F2NHERF1PLCG2PARP14 | |
| SCHEMBL6710524 | 0.91 | PLCG2 (0.38) | NHERF1PLCG2PARP14LMNAMAPT | |
| SCHEMBL6710173 | 0.90 | KMT2A (0.47) | NHERF1PARP14LMNAALDH1A1HPGD | |
| SCHEMBL6707755 | 0.90 | PARP14 (0.43) | NHERF1PLCG2PARP14LMNAALDH1A1 | |
| SCHEMBL6713328 | 0.90 | NHERF1 (0.40) | NHERF1PLCG2PARP14LMNAALDH1A1 | |
| SCHEMBL6712041 | 0.89 | LMNA (0.41) | NHERF1PLCG2PARP14LMNAALDH1A1 | |
| SCHEMBL6708820 | 0.89 | PARP14 (0.41) | NHERF1PLCG2PARP14LMNAALDH1A1 | |
| SCHEMBL6714191 | 0.89 | PARP14 (0.45) | NHERF1PLCG2PARP14LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GALR3 4874/4885NR2F2 1512/4885NHERF1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.