Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711786 | 0.94 | TNIK (0.38) | TNIKLRRK2CSF1RTP53POLB | |
| SCHEMBL6708933 | 0.89 | LRRK2 (0.38) | LRRK2HIF1A | |
| SCHEMBL6713466 | 0.89 | GPR27 (0.39) | PGRHIF1A | |
| SCHEMBL6707764 | 0.88 | HIF1A (0.41) | POLBCSNK2A1HIF1A | |
| SCHEMBL6708665 | 0.88 | IMPDH2 (0.35) | LRRK2HIF1A | |
| SCHEMBL6708095 | 0.88 | MEN1 (0.39) | — | |
| SCHEMBL6709880 | 0.88 | TNIK (0.35) | TNIKMAPTCSNK2A1HIF1A | |
| SCHEMBL6708048 | 0.86 | TNIK (0.36) | TNIKLRRK2CSF1RTP53POLB | |
| SCHEMBL6709855 | 0.85 | F2 (0.43) | LRRK2HIF1A | |
| SCHEMBL6707642 | 0.85 | LRRK2 (0.37) | LRRK2TP53POLBMAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | TNIK 1147/4885LRRK2 4612/4885CSF1R 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.