Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919439 | 0.95 | LMNA (0.38) | IMPDH2AURKAAURKBLRRK2HIF1A | |
| SCHEMBL6711824 | 0.94 | IMPDH2 (0.37) | IMPDH2AURKAAURKBPTPN2PTPN1 | |
| SCHEMBL6710314 | 0.90 | HIF1A (0.41) | AURKAAURKBPTPN2PTPN1PTPN5 | |
| SCHEMBL6713466 | 0.90 | GPR27 (0.39) | AURKAPTPN2PTPN1PTPN5HIF1A | |
| SCHEMBL6713076 | 0.90 | AURKA (0.35) | AURKAAURKBPTPN2PTPN1PTPN5 | |
| SCHEMBL6714137 | 0.88 | LMNA (0.43) | AURKALRRK2HIF1ARORC | |
| SCHEMBL6710477 | 0.88 | TNIK (0.38) | LRRK2HIF1A | |
| SCHEMBL6713561 | 0.87 | BRD4 (0.38) | IMPDH2AURKAAURKBPTPN2PTPN1 | |
| SCHEMBL6709855 | 0.86 | F2 (0.43) | LRRK2HIF1A | |
| SCHEMBL6709230 | 0.85 | GPR27 (0.41) | PTPN2PTPN1PTPN5BRAFHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | IMPDH2 2523/4885AURKA 3954/4885AURKB 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.