Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779970 | 0.77 | F2 (0.42) | LMNASMN1; SMN2TSHRCYP3A4DDB1 | |
| SCHEMBL26934662 | 0.77 | F2 (0.42) | LMNASMN1; SMN2TSHRCYP3A4DDB1 | |
| SCHEMBL6712345 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL14045705 | 0.70 | ALDH1A1 (0.52) | LMNAALDH1A1BLMSMN1; SMN2MAOB | |
| SCHEMBL23747126 | 0.68 | LMNA (0.40) | LMNAALDH1A1BLMSMN1; SMN2MAOB | |
| SCHEMBL19715652 | 0.67 | ALDH1A1 (0.49) | LMNAALDH1A1BLMSMN1; SMN2MAOB | |
| Hydrochloric Acid SCHEMBL4533102 | 0.67 | ALDH1A1 (0.49) | LMNAALDH1A1BLMSMN1; SMN2MAOB | |
| Dibemethine SCHEMBL2139708 | 0.67 | ALDH1A1 (0.67) | LMNAALDH1A1BLMSMN1; SMN2MAOB | |
| Hydrochloric Acid SCHEMBL11228416 | 0.67 | DDB1 (0.43) | LMNAALDH1A1BLMSMN1; SMN2MAOB | |
| SCHEMBL522763 | 0.66 | SLC18A3 (0.49) | LMNAALDH1A1BLMSMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040030131-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030131-A1 | Pharmaceutical compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PYM1, CHRM1 | LMNA 2127/4885ALDH1A1 789/4885BLM 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.