SCHEMBL671107

SCHEMBL671107

C=C(CC=CC#N)C(=O)OC.C=CC=CC=Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.38
APP P05067 2/20 0.38
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
MAPT P10636 3/20 0.34
MCL1 Q07820 2/20 0.34
PAM P19021 1/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296286 0.91 PAM (0.40) LMNAAPPMAPTPAMALDH1A1
SCHEMBL10361556 0.87 PAM (0.38) LMNAHDAC3HDAC4HDAC1HDAC7
Styrene SCHEMBL465033 0.86 ALDH1A1 (0.36) LMNAMAPTPAMALDH1A1KDM4E
SCHEMBL8181484 0.85 LMNA (0.40) LMNAAPPHDAC3HDAC4HDAC1
SCHEMBL9717067 0.85 LMNA (0.41) LMNAAPPMAPTMCL1ALDH1A1
SCHEMBL5999282 0.84 LMNA (0.46) LMNAAPPMAPTMCL1ALDH1A1
Acrylonitrile SCHEMBL3797624 0.82 PAM (0.44) LMNAMAPTPAMALDH1A1KDM4E
Acrylonitrile SCHEMBL3628806 0.82 PAM (0.46) LMNAHDAC1MAPTPAMALDH1A1
Styrene SCHEMBL7169692 0.81 ALDH1A1 (0.33) LMNAMAPTPAMALDH1A1KDM4E
Acrylonitrile SCHEMBL9631539 0.80 LMNA (0.41) LMNAAPPHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640044-A1 A PROCESS FOR MAKING A MULTILAYER FLEXOGRAPHIC PRINTING PLATE. DU PONT (US) 1995-03-01 EP claimed
WO-1993023253-A1 A PROCESS FOR MAKING A MULTILAYER FLEXOGRAPHIC PRINTING PLATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-11-25 WO claimed
EP-3640275-B1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SHPP GLOBAL TECH BV (NL) 2022-06-29 EP disclosed
EP-3640275-A1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SABIC Global Technologies B.V. (NL) 2020-04-22 EP disclosed
CN-111040130-A Curable high heat epoxy compositions, cured epoxy compositions thereof, methods of manufacture thereof, and articles comprising the same 沙特基础工业全球技术有限公司 2020-04-21 CN disclosed
US-20200115544-A1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-16 US disclosed
EP-2291454-B1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP disclosed
US-8067493-B2 Polymer compositions, method of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-29 US disclosed
US-8034866-B2 Polyester, polycarbonate, impact modifier, reinforcing filler, fibrillated fluoropolymer, and antioxidants, mold release agents, colorants, quenchers, or stabilizers; power tool housings; higher modulus, improved ductility, impact strength, melt processability, molding speed; cost efficiency SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-10-11 US disclosed
EP-2291454-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC Innovative Plastics IP B.V. (NL) 2011-03-09 EP disclosed
EP-2276809-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC Innovative Plastics IP B.V. (NL) 2011-01-26 EP disclosed
WO-2009137627-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-12 WO disclosed
WO-2009137626-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-12 WO disclosed
US-20080246181-A1 Polymer Compositions, Method of Manufacture, and Articles Formed Therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-09 US disclosed
US-20080242789-A1 Polymer Compositions, Method of Manufacture, and Articles Formed Therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-10-02 US disclosed
US-20080095968-A1 Method for producing a micro or nano mechanical part comprising a femtolaser-assisted ablation step TAG HEUER SA (CH) 2008-04-24 US disclosed
US-4117035-A CLARITY, FOR MEDICAL PRODUCTS ABBOTT LABORATORIES (US) 1978-09-26 US disclosed
US-4096201-A BUTADIENE-ACRYLONITRILE COPOLYMER, HYDROXYALKYL METHACRYLATE, ALKYL METHACRYLATE, ORGANIC HYDROPEROXIDE DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1978-06-20 US disclosed