Styrene

Styrene

SCHEMBL7169692

C=CC#N.C=CC=CCC(=C)C(=O)OC.C=Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.32
HIF1A Q16665 1/20 0.31
MEN1 O00255 4/20 0.31
KMT2A Q03164 4/20 0.31
MAPT P10636 3/20 0.31
PAM P19021 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2019985 0.93 ALDH1A1 (0.39) ALDH1A1TSHRLMNAHIF1AMEN1
Styrene SCHEMBL465033 0.86 ALDH1A1 (0.36) ALDH1A1TSHRLMNAPOLBHIF1A
Styrene SCHEMBL7169689 0.86 ALDH1A1 (0.38) ALDH1A1TSHRPAM
Acrylonitrile SCHEMBL17360697 0.86 ALDH1A1 (0.31) ALDH1A1
Acrylonitrile SCHEMBL3797624 0.85 PAM (0.44) ALDH1A1LMNAPOLBMEN1KMT2A
Acrylonitrile SCHEMBL3628806 0.85 PAM (0.46) ALDH1A1LMNAPOLBMEN1KMT2A
SCHEMBL296286 0.81 PAM (0.40) ALDH1A1LMNAPOLBMEN1KMT2A
SCHEMBL671107 0.81 LMNA (0.38) ALDH1A1LMNAMAPTPAMKDM4E
Styrene SCHEMBL296287 0.80 ALDH1A1 (0.42) ALDH1A1TSHRLMNAPOLBMAPT
Styrene SCHEMBL1069594 0.80 ALDH1A1 (0.42) ALDH1A1TSHRLMNAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1290076-A1 COMPOSITIONS AND ARTICLES CONTAINING STYRENE POLYMERS AND COPOLYMERS AND BLENDS THEREOF GENERAL ELECTRIC COMPANY (US) 2003-03-12 EP claimed
WO-2001090231-A1 COMPOSITIONS AND ARTICLES CONTAINING STYRENE POLYMERS AND COPOLYMERS AND BLENDS THEREOF GENERAL ELECTRIC COMPANY (US) 2001-11-29 WO claimed