Styrene

Styrene

SCHEMBL465033

C=C(CC=CC#N)C(=O)OC.C=Cc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
TSHR P16473 1/20 0.36
POLB P06746 2/20 0.33
LMNA P02545 2/20 0.33
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
PAM P19021 1/20 0.33
HIF1A Q16665 1/20 0.32
ATM Q13315 1/20 0.32
MAPT P10636 3/20 0.32
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7169692 0.86 ALDH1A1 (0.33) ALDH1A1TSHRPOLBLMNAKMT2A
SCHEMBL671107 0.86 LMNA (0.38) ALDH1A1LMNAPAMMAPTKDM4E
SCHEMBL5998509 0.85 ELANE (0.36) ALDH1A1TSHRLMNAKMT2AMAPT
SCHEMBL1318461 0.83 ALDH1A1 (0.35) ALDH1A1TSHR
Acrylonitrile SCHEMBL3628806 0.83 PAM (0.46) ALDH1A1POLBLMNAKMT2AMEN1
Styrene SCHEMBL448561 0.83 ALDH1A1 (0.39) ALDH1A1TSHRLMNAKMT2AMEN1
Styrene SCHEMBL2019985 0.83 ALDH1A1 (0.39) ALDH1A1TSHRLMNAKMT2AMEN1
Styrene SCHEMBL17836838 0.83 ALDH1A1 (0.39) ALDH1A1TSHRLMNAPAMMAPT
Itaconate SCHEMBL16779982 0.83 TSHR (0.39) TSHRKDM4ETDP1L3MBTL1
Styrene SCHEMBL28052240 0.82 ALDH1A1 (0.44) ALDH1A1TSHRLMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112063146-A PC/PMMA alloy and preparation method and application thereof 广州华新科智造技术有限公司 2020-12-11 CN claimed
US-7144981-B2 Process for separating volatile components from polymers BAYER AKTIENGESELLSCHAFT (DE) 2006-12-05 US claimed
US-20040255780-A1 Process for separating volatile components from polymers LANXESS DEUTSCHLAND GMBH (DE) 2004-12-23 US claimed
EP-0697438-B1 Graft copolymers of propylene polymer material impact modified with a heterophasic olefin polymer material MONTELL NORTH AMERICA INC (US) 1998-06-03 EP claimed
EP-0697438-A1 Graft copolymers of propylene polymer material impact modified with a heterophasic olefin polymer material MONTELL NORTH AMERICA INC. (US) 1996-02-21 EP claimed
EP-0479171-B1 Blends of a graft copolymer of propylene polymer material with a graft copolymer of olefinic rubber material MONTELL NORTH AMERICA INC (US) 1995-11-15 EP claimed
US-5455300-A Polypropylene grafted with an aromatic and/or acrylate and an acrylic monomer blended with a propylene or ethylene/propylene polymer; weldline strength; durability MONTELL NORTH AMERICA INC. (US) 1995-10-03 US claimed
US-5397836-A Thermoplastic blend with synthetic rubbers for molding materials with tensile strength HIMONT INCORPORATED (US) 1995-03-14 US claimed
US-5286791-A Impact modified graft copolymer compositions containing broad molecular weight distribution polypropylene HIMONT INCORPORATED (US) 1994-02-15 US claimed
EP-0479171-A2 Blends of a graft copolymer of propylene polymer material with a graft copolymer of olefinic rubber material MONTELL NORTH AMERICA INC. (US) 1992-04-08 EP claimed
EP-0472898-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-03-04 EP claimed
CN-112063146-A PC/PMMA alloy and preparation method and application thereof 广州华新科智造技术有限公司 2020-12-11 CN disclosed
US-8928976-B2 Resin composition and optical film formed by using the same LG CHEM, LTD. (KR) 2015-01-06 US disclosed
EP-2418246-B1 AUTOMOBILE INTERIOR PART WITH REDUCED SQUEAKING NOISES TECHNO POLYMER CO LTD (JP) 2014-08-20 EP disclosed
US-20130314785-A1 RESIN COMPOSITION AND OPTICAL FILM FORMED BY USING THE SAME LG CHEM, LTD. (KR) 2013-11-28 US disclosed
US-4117034-A SYNERGISTIC ENHANCEMENT OF IMPACT PROPERTIES BORG-WARNER CORPORATION (US) 1978-09-26 US disclosed
US-4117034-A SYNERGISTIC ENHANCEMENT OF IMPACT PROPERTIES BORG-WARNER CORPORATION (US) 1978-09-26 US disclosed
US-4065522-A GRAFT POLYMERS, COPOLYMERIZATION WITH A METAL SALT OF AN UNSATURATED SULFONIC ACID BORG-WARNER CORPORATION (US) 1977-12-27 US disclosed
US-3950455-A RUBBER LATEX, BULK POLYMERIZATION TORAY INDUSTRIES, INC. (JA) 1976-04-13 US disclosed
US-3943159-A Process for the production of telomers containing isocyanate groups BAYER AKTIENGESELLSCHAFT (DT) 1976-03-09 US disclosed