Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711208 | 0.71 | ADRB1 (0.43) | ADRB1SIRT6ALDH1A1USP2TSHR | |
| Isophthalic Acid SCHEMBL27478330 | 0.67 | ADRB1 (0.69) | ADRB1SIRT6ALDH1A1USP2TSHR | |
| SCHEMBL9050102 | 0.66 | NR3C1 (0.45) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL7526992 | 0.66 | SIRT6 (1.00) | ADRB1SIRT6ALDH1A1HTR1APOLB | |
| SCHEMBL336262 | 0.66 | SIRT6 (1.00) | ADRB1SIRT6ALDH1A1HTR1APOLB | |
| SCHEMBL6151805 | 0.64 | SIRT6 (0.96) | ADRB1SIRT6ALDH1A1HTR1APOLB | |
| Hydrochloric Acid SCHEMBL1814630 | 0.64 | SIRT6 (0.96) | ADRB1SIRT6ALDH1A1HTR1APOLB | |
| SCHEMBL6152151 | 0.64 | SIRT6 (0.96) | ADRB1SIRT6ALDH1A1HTR1APOLB | |
| SCHEMBL1496058 | 0.64 | SIRT6 (0.96) | ADRB1SIRT6ALDH1A1HTR1APOLB | |
| Hydrogen Sulfide SCHEMBL28002215 | 0.64 | SIRT6 (0.96) | ADRB1SIRT6ALDH1A1HTR1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092524-A1 | Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same | PIERRE FABRE MEDICAMENT (FR) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092524-A1 | Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same | CBR3, CBR1, HCCS | ADRB1 939/4885SIRT6 121/4885ALDH1A1 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.