Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | CHAT | P28329 | 5/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631682 | 0.84 | APP (0.46) | RAB9AMEN1KMT2ANPC1POLB | |
| Iodide SCHEMBL7758712 | 0.83 | APP (0.47) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL3748599 | 0.78 | RAB9A (0.60) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL4567105 | 0.78 | RAB9A (0.60) | RAB9AMEN1KMT2ANPC1POLB | |
| Iodide SCHEMBL592266 | 0.77 | RAB9A (0.62) | RAB9AMEN1KMT2ANPC1POLB | |
| Iodide SCHEMBL10843215 | 0.77 | RAB9A (0.62) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL8740741 | 0.75 | RELA (0.44) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL9124614 | 0.74 | RELA (0.47) | MEN1KMT2ANPC1BCHEACHE | |
| SCHEMBL4243407 | 0.73 | ALDH1A1 (0.61) | RAB9AMEN1KMT2ANPC1GFER | |
| SCHEMBL9192952 | 0.73 | ALDH1A1 (0.61) | RAB9AMEN1KMT2ANPC1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242416-A1 | Compositions and methods for intracellular delivery | YISSUM, RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-12-02 | — | — | US | disclosed |
| EP-1411897-A2 | COMPOSITIONS AND METHODS FOR INTRACELLULAR DELIVERY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003000174-A2 | COMPOSITIONS AND METHODS FOR INTRACELLULAR DELIVERY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-01-03 | — | — | WO | disclosed |