Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634573 | 0.85 | HCAR3 (0.56) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14339589 | 0.84 | ALDH1A1 (0.45) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4967594 | 0.81 | MAPT (0.62) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3928138 | 0.81 | MAPT (0.51) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3928131 | 0.81 | MAPT (0.51) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT | |
| Ammonia Solution, Strong SCHEMBL6712648 | 0.80 | MAPT (0.52) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL23579537 | 0.79 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2HTTHCAR3 | |
| SCHEMBL29974854 | 0.79 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2HTTHCAR3 | |
| SCHEMBL23997424 | 0.78 | ALDH1A1 (0.51) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3966385 | 0.78 | HTT (0.60) | L3MBTL1MAPTALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192748-A1 | Heterocyclic compounds | BOEHRINGER INGELHEIM PARMACEUTICALS, INC. | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192748-A1 | Heterocyclic compounds | IL1B, CCL5, IL4 | L3MBTL1 3569/4885MAPT 3685/4885ALDH1A1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.