Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | BLM | P54132 | 5/20 | 0.47 |
| ▸ | THPO | P40225 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713203 | 0.79 | ALDH1A1 (0.64) | LMNAHPGDGAANFKB1TDP1 | |
| SCHEMBL29929036 | 0.79 | XDH (0.65) | XDHCA1CA2CA4CA6 | |
| SCHEMBL891837 | 0.79 | XDH (0.65) | XDHCA1CA2CA4CA6 | |
| SCHEMBL1387883 | 0.77 | ESR1 (0.44) | CA2KDM4EBLMTDP1TRPA1 | |
| SCHEMBL26249726 | 0.76 | XDH (0.68) | XDHCA1CA2CA4CA6 | |
| SCHEMBL28140503 | 0.74 | ENPP2 (0.48) | CA2MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL10403571 | 0.72 | XDH (0.63) | XDHCA1CA2CA4CA6 | |
| SCHEMBL5833388 | 0.72 | XDH (0.63) | XDHCA1CA2CA4CA6 | |
| SCHEMBL3217327 | 0.72 | CA1 (0.56) | XDHCA1CA2CA4CA6 | |
| Hydroxychavicol SCHEMBL43300 | 0.72 | XDH (1.00) | XDHCA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097436-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-05-20 | — | — | US | claimed |
| US-6689767-B2 | TRITERPENE BACTERICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-02-10 | — | — | US | claimed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | claimed |
| WO-2002026762-A1 | TRITERPENES HAVING ANTIBACTERIAL ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | claimed |
| US-20040097436-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-05-20 | — | — | US | disclosed |
| US-6689767-B2 | TRITERPENE BACTERICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-02-10 | — | — | US | disclosed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | disclosed |
| WO-2002026762-A1 | TRITERPENES HAVING ANTIBACTERIAL ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097436-A1 | Triterpenes having antibacterial activity | BET1, PGGT1B, LSS | XDH 458/4885CA1 4376/4885CA2 4451/4885 |
| US-20020119935-A1 | Triterpenes having antibacterial activity | BET1, PGGT1B, LSS | XDH 458/4885CA1 4376/4885CA2 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.