Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146357 | 0.87 | HTR2A (0.54) | HTR2ATAAR1HTR2C | |
| SCHEMBL5773325 | 0.86 | HTR2A (0.39) | HTR2ATAAR1HTR2CP2RX3P2RX2 | |
| SCHEMBL6114675 | 0.79 | DUT (0.34) | — | |
| SCHEMBL21367294 | 0.77 | DUT (0.37) | — | |
| SCHEMBL3865025 | 0.76 | DUT (0.37) | — | |
| SCHEMBL22234089 | 0.75 | PYCR1 (0.41) | HTR2A | |
| SCHEMBL4337045 | 0.75 | KDM4E (0.43) | — | |
| SCHEMBL2497072 | 0.75 | HTT (0.44) | — | |
| SCHEMBL6712170 | 0.75 | IDO1 (0.36) | TAAR1 | |
| SCHEMBL6713069 | 0.74 | HTR2A (0.38) | HTR2ATAAR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | PFIZER INC. | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077853-A1 | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines | NOS3, NOS1, NOS2 | HTR2A 816/4885TAAR1 572/4885HTR2C 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.