Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | SORD | Q00796 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6714596 | 0.84 | HRH4 (0.56) | HRH4HTR1AHTR1BSORDADRA1D | |
| Hydrochloric Acid SCHEMBL6712709 | 0.81 | HTR1A (0.54) | HTR1AHTR2CDRD2DRD3 | |
| SCHEMBL6712772 | 0.81 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL6714260 | 0.79 | HTR1A (0.55) | HTR1ADRD2DRD3 | |
| SCHEMBL6714160 | 0.76 | HRH4 (0.67) | HRH4HTR1AHTR1BSORDHTR1D | |
| SCHEMBL6714657 | 0.75 | HRH4 (0.55) | HRH4HTR1AHTR1BADRA1DADRA1A | |
| SCHEMBL7085853 | 0.75 | HRH4 (0.55) | HRH4HTR1AHTR1BSORDADRA1D | |
| SCHEMBL605232 | 0.75 | HRH4 (1.00) | HRH4SORDHTR2C | |
| SCHEMBL9224900 | 0.74 | HRH4 (0.63) | HRH4HTR1AHTR1BSORDHTR1D | |
| SCHEMBL6711645 | 0.74 | ALDH1A1 (0.48) | HTR1AADRA1DADRA1AADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138203-A1 | Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia | STEINER GERD | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138203-A1 | Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia | HTR1A, HTR5A, HTR2C | HRH4 937/4885HTR1A 1/4885HTR1B 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.