Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.57 |
| ▸ | UNG | P13051 | 1/20 | 0.51 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | NAT1 | P18440 | 3/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | DDT | P30046 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952773 | 1.00 | TRIM24 (0.57) | TRIM24TRIM33UNGHNF4ANAT1 | |
| SCHEMBL2559209 | 0.86 | TRIM24 (0.53) | TRIM24TRIM33UNGHNF4ANAT1 | |
| SCHEMBL689031 | 0.84 | HNF4A (0.62) | HNF4ALMNAPTPN1MYCBCAT2 | |
| SCHEMBL2556018 | 0.82 | TRIM24 (0.49) | TRIM24TRIM33UNGHNF4ANAT1 | |
| SCHEMBL13250832 | 0.82 | TRIM24 (0.53) | TRIM24TRIM33UNGNAT1KDM4E | |
| SCHEMBL5490744 | 0.82 | TRIM24 (0.52) | TRIM24TRIM33UNGNAT1KDM4E | |
| SCHEMBL2554784 | 0.81 | TRIM24 (0.51) | TRIM24TRIM33UNGNAT1KDM4E | |
| SCHEMBL2560114 | 0.81 | TRIM24 (0.51) | TRIM24TRIM33UNGNPC1RAB9A | |
| SCHEMBL2562602 | 0.81 | TRIM24 (0.51) | TRIM24TRIM33UNGNAT1KDM4E | |
| SCHEMBL2561114 | 0.81 | TRIM24 (0.51) | TRIM24TRIM33UNGNAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | TRIM24 4180/4885TRIM33 4502/4885UNG 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.