Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 7/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650605 | 0.87 | CYP11B2 (0.38) | CYP11B2CYP11B1ABL1KITPDGFRA | |
| SCHEMBL6645525 | 0.75 | C1S (0.43) | CYP11B2CYP11B1ABL1CYP1A2CYP17A1 | |
| SCHEMBL7259043 | 0.69 | CYP1A2 (0.48) | CYP11B2CYP11B1ABL1KITPDGFRA | |
| SCHEMBL6648528 | 0.68 | MAPK13 (0.40) | CYP11B2CYP11B1ABL1CYP1A2CYP2E1 | |
| SCHEMBL21757521 | 0.66 | OPRL1 (0.48) | CYP11B2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21757505 | 0.66 | OPRL1 (0.48) | CYP11B2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6628333 | 0.66 | JAK3 (0.39) | CYP11B2CYP11B1ABL1CYP1A2CYP17A1 | |
| SCHEMBL6650148 | 0.65 | PTGS2 (0.42) | CYP11B2CYP11B1ABL1PDE10ACYP17A1 | |
| SCHEMBL2755231 | 0.64 | NPY5R (0.37) | CYP11B2CYP11B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL21757517 | 0.64 | OPRL1 (0.49) | CYP11B2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040267017-A1 | 3-pyridyl or 4-isoquinolinyl thiazoles as c17, 20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267017-A1 | 3-pyridyl or 4-isoquinolinyl thiazoles as c17, 20 lyase inhibitors | CYP17A1, CYP21A2, HSD17B1 | CYP11B2 45/4885CYP11B1 27/4885ABL1 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.