Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6717100 | 0.94 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL6717109 | 0.94 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAHTTKMT2A | |
| Formic Acid SCHEMBL6713928 | 0.87 | CRHBP (0.58) | ALDH1A1MAPTLMNAHTTROCK2 | |
| SCHEMBL23611205 | 0.84 | ROCK2 (0.56) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL23611208 | 0.84 | ROCK2 (0.56) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL4982071 | 0.82 | POLB (0.66) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL19074543 | 0.82 | POLB (0.66) | ALDH1A1MAPTLMNAHTTKMT2A | |
| Formic Acid SCHEMBL6722850 | 0.82 | RAB9A (0.52) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| Dimethylamine SCHEMBL6726772 | 0.81 | POLB (0.59) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8010089 | 0.81 | POLB (0.63) | ALDH1A1MAPTLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | SLC1A2, SLC6A7, SLC1A1 | ALDH1A1 572/4885MAPT 427/4885LMNA 3700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.