Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.59 |
| ▸ | DRD4 | P21917 | 9/20 | 0.59 |
| ▸ | DRD3 | P35462 | 9/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711688 | 0.94 | HRH4 (0.52) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6977709 | 0.94 | GRIN1 (0.66) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6715832 | 0.90 | HTR1A (0.63) | DRD2DRD4DRD3HRH4HTR1A | |
| SCHEMBL6978625 | 0.88 | GRIN1 (0.58) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL7087322 | 0.87 | HRH4 (0.51) | DRD2DRD4DRD3HRH4ADRA1D | |
| SCHEMBL7084667 | 0.87 | HRH4 (0.51) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6712910 | 0.84 | DRD2 (0.48) | DRD2DRD4DRD3HRH4ADRA1D | |
| SCHEMBL6714648 | 0.84 | HTR1A (0.49) | DRD2DRD4HRH4ADRA1DADRA1A | |
| SCHEMBL6973851 | 0.83 | DRD2 (0.59) | DRD2DRD4DRD3HRH4HTR1A | |
| Hydrochloric Acid SCHEMBL6711485 | 0.82 | DRD2 (0.57) | DRD2DRD4DRD3HRH4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138203-A1 | Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia | STEINER GERD | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138203-A1 | Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia | HTR1A, HTR5A, HTR2C | DRD2 83/4885DRD4 150/4885DRD3 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.