Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 3/20 | 0.46 |
| ▸ | GABRD | O14764 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.46 |
| ▸ | GABRE | P78334 | 3/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719869 | 0.99 | PLA2G4A (0.58) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL29660260 | 0.99 | PLA2G4A (0.58) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL10921361 | 0.91 | PLA2G4A (0.56) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL6716653 | 0.90 | MEN1 (0.50) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL3676424 | 0.90 | GPR84 (0.58) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL29251326 | 0.88 | MEN1 (0.53) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL30844114 | 0.88 | MEN1 (0.53) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL30844112 | 0.87 | MEN1 (0.55) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL29251786 | 0.87 | MEN1 (0.55) | PLA2G4ALTB4RMEN1KMT2ANQO2 | |
| SCHEMBL29251322 | 0.85 | MEN1 (0.50) | PLA2G4ALTB4RMEN1KMT2ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186300-A1 | Process for the preparation of zafirlukast | FINETECH LABORATORIES LTD. (IL) | 2004-09-23 | — | — | US | disclosed |
| WO-2002046153-A2 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST | FINETECH LABORATORIES LTD. (IL) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186300-A1 | Process for the preparation of zafirlukast | LTC4S, LTB4R, CMA1 | PLA2G4A 466/4885LTB4R 2/4885MEN1 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.