Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671040 | 0.87 | LMNA (0.62) | NPSR1DHFRLMNA | |
| SCHEMBL670722 | 0.83 | DHFR (0.62) | NPSR1DHFRLMNA | |
| SCHEMBL18601588 | 0.77 | DHFR (0.53) | NPSR1DHFRLMNA | |
| SCHEMBL670828 | 0.76 | DHFR (0.61) | NPSR1DHFRLMNA | |
| SCHEMBL671193 | 0.76 | DHFR (0.59) | NPSR1DHFRLMNA | |
| SCHEMBL670315 | 0.75 | NPSR1 (0.63) | NPSR1DHFRLMNA | |
| SCHEMBL670945 | 0.74 | DHFR (0.53) | NPSR1DHFRLMNA | |
| SCHEMBL669999 | 0.74 | DHFR (0.58) | NPSR1DHFRLMNA | |
| SCHEMBL671090 | 0.74 | DHFR (0.62) | NPSR1DHFRLMNA | |
| SCHEMBL4097563 | 0.70 | NPSR1 (0.97) | NPSR1DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11844802-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2023-12-19 | — | — | US | disclosed |
| US-20230044670-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | UNIV EMORY (US) | 2023-02-09 | — | — | US | disclosed |
| US-11471461-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2022-10-18 | — | — | US | disclosed |
| US-20210100806-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | UNIV EMORY (US) | 2021-04-08 | — | — | US | disclosed |
| US-10888565-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2021-01-12 | — | — | US | disclosed |
| US-20200121687-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | UNIV EMORY (US) | 2020-04-23 | — | — | US | disclosed |
| US-20180207166-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-07-26 | — | — | US | disclosed |
| US-9808464-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| EP-3187197-A1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | Emory University (US) | 2017-07-05 | — | — | EP | disclosed |
| EP-2605804-B1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | UNIV EMORY (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170035771-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-02-09 | — | — | US | disclosed |
| US-9511071-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2016-12-06 | — | — | US | disclosed |
| EP-2605804-A2 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | Emory University (US) | 2013-06-26 | — | — | EP | disclosed |
| US-20130137634-A1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2013-05-30 | — | — | US | disclosed |
| WO-2012024489-A2 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10888565-B2 | Compounds and compositions for ossification and methods related thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-20130137634-A1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-20180207166-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-11471461-B2 | Compounds and compositions for ossification and methods related thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-20230044670-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-20210100806-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-20170035771-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-20200121687-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
| US-11844802-B2 | Compounds and compositions for ossification and methods related thereto | BMP2, SOST, BMP4 | NPSR1 2764/4885DHFR 3180/4885LMNA 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.