Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28748164 | 0.89 | KDM4C (0.40) | KDM4CCXCR2KDM4EASPHKDM8 | |
| SCHEMBL15420776 | 0.84 | ALOX5 (0.47) | CXCR2TP53KDM4EGAAALDH1A1 | |
| SCHEMBL28511317 | 0.84 | ALOX5 (0.47) | CXCR2TP53KDM4EGAAALDH1A1 | |
| SCHEMBL18398628 | 0.84 | ALOX5 (0.47) | CXCR2TP53KDM4EGAAALDH1A1 | |
| SCHEMBL1044302 | 0.80 | CYP2D6 (0.49) | KDM4CKDM4EASPHKDM8CYP2D6 | |
| SCHEMBL6719047 | 0.80 | CYP2D6 (0.46) | KDM4CKDM4EASPHKDM8CYP2D6 | |
| SCHEMBL6725960 | 0.80 | CYP2D6 (0.49) | KDM4CKDM4EASPHKDM8CYP2D6 | |
| SCHEMBL17339199 | 0.80 | CYP2D6 (0.46) | KDM4CKDM4EASPHKDM8CYP2D6 | |
| SCHEMBL6353089 | 0.76 | ALOX5 (0.47) | CXCR2TP53KDM4ECYP1A2CYP3A4 | |
| SCHEMBL15420512 | 0.76 | ALOX5 (0.47) | CXCR2TP53KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835841-B2 | Asymmetric catalytic hydrogenation process for preparation of chiral cyclic β-aminoesters | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-28 | — | — | US | disclosed |
| US-20040082795-A1 | Asymmetric catalytic hydrogenation process for preparation of chiral cyclic beta-aminoesters | BRISTOL-MYERS SQUIBB COMPANY | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082795-A1 | Asymmetric catalytic hydrogenation process for preparation of chiral cyclic beta-aminoesters | ADAM17, ADAM9, ADAM12 | KDM4C 2943/4885CXCR2 1994/4885TP53 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.