Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ASPH | Q12797 | 2/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044302 | 1.00 | CYP2D6 (0.49) | CYP2D6KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL17339199 | 0.97 | CYP2D6 (0.46) | CYP2D6KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL6719047 | 0.97 | CYP2D6 (0.46) | CYP2D6KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL18946078 | 0.84 | SLC6A3 (0.46) | CYP2D6KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL10305737 | 0.84 | RECQL (0.44) | KDM4EMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10137636 | 0.82 | ALOX5 (0.50) | CYP2D6KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL4431629 | 0.82 | ALOX5 (0.50) | CYP2D6KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL4431627 | 0.82 | ALOX5 (0.50) | CYP2D6KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL17339168 | 0.81 | DHODH (0.46) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28748164 | 0.80 | KDM4C (0.40) | CYP2D6KDM4EMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835841-B2 | Asymmetric catalytic hydrogenation process for preparation of chiral cyclic β-aminoesters | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-28 | — | — | US | disclosed |
| US-20040082795-A1 | Asymmetric catalytic hydrogenation process for preparation of chiral cyclic beta-aminoesters | BRISTOL-MYERS SQUIBB COMPANY | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082795-A1 | Asymmetric catalytic hydrogenation process for preparation of chiral cyclic beta-aminoesters | ADAM17, ADAM9, ADAM12 | CYP2D6 1715/4885KDM4E 2512/4885MEN1 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.