Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 10/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368880 | 0.82 | TDP1 (0.55) | LMNATDP1PPARARECQLMAPT | |
| SCHEMBL7614913 | 0.77 | S1PR1 (0.55) | ALDH1A1LMNALTA4HRAB9A | |
| SCHEMBL6716118 | 0.77 | L3MBTL1 (0.53) | ALDH1A1LMNAPPARAPPARGPPARD | |
| SCHEMBL6715108 | 0.75 | L3MBTL1 (0.51) | ALDH1A1LMNAPPARAPPARGPPARD | |
| SCHEMBL11068766 | 0.75 | TDP1 (0.48) | ALDH1A1LMNATDP1PPARARECQL | |
| SCHEMBL7616391 | 0.75 | S1PR1 (0.52) | ALDH1A1LMNALTA4HPPARAPPARG | |
| SCHEMBL6714987 | 0.74 | LTA4H (0.51) | ALDH1A1LMNALTA4H | |
| SCHEMBL7619648 | 0.73 | S1PR1 (0.53) | ALDH1A1LMNALTA4HPPARAPPARG | |
| SCHEMBL4419400 | 0.73 | ALDH1A1 (0.62) | ALDH1A1LMNARECQLMMP8MAPT | |
| SCHEMBL20350502 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNARECQLMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | ALDH1A1 3508/4885LMNA 4239/4885TDP1 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.