Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427462 | 0.84 | MMP8 (0.47) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL457731 | 0.81 | PKM (0.40) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL7406644 | 0.79 | PKM (0.39) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| Water SCHEMBL10546251 | 0.79 | MEN1 (0.40) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL3903236 | 0.78 | MMP8 (0.43) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL3903232 | 0.78 | MMP8 (0.43) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL31423716 | 0.78 | MMP8 (0.43) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL3906498 | 0.78 | MMP8 (0.43) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL8160331 | 0.78 | ALDH1A1 (0.44) | MMP8CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL8165932 | 0.78 | ALDH1A1 (0.36) | MMP8CYP4F2CYP4A11ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-6020502-A | Preparation of fluorinated dicarbonyls | BNFL FLUOROCHEMICALS LTD. (GB) | 2000-02-01 | — | — | US | disclosed |
| EP-0738248-A1 | THE PREPARATION OF DICARBONYLS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995014646-A1 | THE PREPARATION OF DICARBONYLS | BNFL FLUOROCHEMICALS LTD (GB) | 1995-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | MMP8 4878/4885CYP4F2 907/4885CYP4A11 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.