Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 6/20 | 0.46 |
| ▸ | RXRG | P48443 | 6/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718854 | 0.93 | AGXT (0.49) | RXRANR1H2NR1H3RXRBRXRG | |
| SCHEMBL6717904 | 0.87 | ENPP2 (0.50) | AGXTPTPN1FFAR1FFAR4PPARD | |
| SCHEMBL6719678 | 0.86 | NR1H2 (0.45) | RXRANR1H2NR1H3RXRBRXRG | |
| SCHEMBL6717797 | 0.85 | HCAR2 (0.42) | RXRARXRBRXRGAGXTFFAR1 | |
| SCHEMBL6719809 | 0.83 | FFAR1 (0.43) | AGXTPTPN1FFAR1FFAR4NR4A2 | |
| SCHEMBL3416605 | 0.80 | S1PR1 (0.53) | RXRANR1H2NR1H3RXRBRXRG | |
| SCHEMBL3416601 | 0.80 | S1PR1 (0.53) | RXRANR1H2NR1H3RXRBRXRG | |
| SCHEMBL13460803 | 0.79 | NR4A2 (0.66) | RXRANR1H2NR1H3FFAR1FFAR4 | |
| SCHEMBL4726499 | 0.79 | PSEN1 (0.46) | RXRARXRBRXRGPPARDPSEN1 | |
| SCHEMBL23296145 | 0.77 | RXRA (0.58) | RXRANR1H2NR1H3RXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | GPR119, NR3C1, INSR | RXRA 31/4885NR1H2 17/4885NR1H3 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.