Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711493 | 0.78 | ALDH1A1 (0.35) | CA2 | |
| SCHEMBL7207381 | 0.78 | ELANE (0.32) | — | |
| SCHEMBL7215625 | 0.71 | — | — | |
| SCHEMBL6703714 | 0.62 | TSHR (0.32) | — | |
| SCHEMBL6506594 | 0.60 | S1PR2 (0.36) | — | |
| SCHEMBL6505233 | 0.59 | ALDH1A1 (0.47) | — | |
| SCHEMBL2994446 | 0.57 | GAA (0.41) | CA2 | |
| SCHEMBL2737003 | 0.57 | RIPK1 (0.59) | — | |
| SCHEMBL12493702 | 0.56 | CA2 (0.44) | CA2 | |
| SCHEMBL12496136 | 0.56 | CA2 (0.39) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004531459-A | — | — | 2004-10-14 | — | — | JP | claimed |
| EP-1366024-A2 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-12-03 | — | — | EP | claimed |
| WO-2002030882-A2 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | claimed |