Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722027 | 1.00 | OPRM1 (0.55) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL6729317 | 0.81 | OPRM1 (0.52) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL6729315 | 0.81 | OPRM1 (0.52) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL410620 | 0.80 | OPRM1 (0.51) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL13303676 | 0.80 | OPRM1 (0.51) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL410110 | 0.80 | OPRM1 (0.51) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL411284 | 0.80 | OPRM1 (0.55) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL410116 | 0.80 | OPRM1 (0.51) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL409665 | 0.80 | OPRM1 (0.51) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL410115 | 0.80 | OPRM1 (0.55) | OPRM1OPRK1OPRD1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040049049-A1 | Stereoselective synthesis of 1,2-disubstituted cycloalkyls | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049049-A1 | Stereoselective synthesis of 1,2-disubstituted cycloalkyls | CYP8B1, AGTR1, AGTR2 | OPRM1 923/4885OPRK1 660/4885OPRD1 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.