Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28986962 | 0.84 | NPC1 (0.59) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2905322 | 0.84 | AHR (0.49) | HSD17B10LMNACA9CA12CA1 | |
| SCHEMBL28732081 | 0.80 | NPC1 (0.58) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30893024 | 0.77 | CYP11B1 (0.44) | MAPK12KDM4ECYP2D6CYP2C9CYP11B1 | |
| SCHEMBL1287806 | 0.74 | CA12 (0.47) | KDM4EHSD17B10LMNACYP11B1CYP11B2 | |
| SCHEMBL31668742 | 0.72 | HSD17B10 (0.42) | HSD17B10CYP2D6CA9CA12CA1 | |
| SCHEMBL634543 | 0.72 | HSD17B10 (0.42) | HSD17B10CYP2D6CA9CA12CA1 | |
| SCHEMBL8944351 | 0.71 | CYP2C19 (0.47) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7323916 | 0.71 | ANPEP (0.41) | HSD17B10LMNACA9CA12CA1 | |
| SCHEMBL16254014 | 0.71 | HSD17B10 (0.46) | HSD17B10LMNACA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248310-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2004-12-09 | — | — | US | claimed |
| US-20030186451-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads. and lateral flow | SMITH JACK V (US) | 2003-10-02 | — | — | US | claimed |
| US-6537823-B1 | Use in determination of adulterants in illicit drug screening samples as a means of detecting false negative results | SCITECK DIAGNOSTICS, INC. | 2003-03-25 | — | — | US | claimed |
| US-20030045003-A1 | Method for detection of the adulterant urine luckTM in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2003-03-06 | — | — | US | claimed |
| US-20030027350-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2003-02-06 | — | — | US | claimed |
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| CN-111587239-A | Method for producing lactam compound and lactam compound produced by same | 基础科学研究院 | 2020-08-25 | — | — | CN | disclosed |
| US-20040248310-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2004-12-09 | — | — | US | disclosed |
| US-20040097728-A1 | Method for producing anellated tetrahydro-{1h}-triazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |
| US-20030186451-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads. and lateral flow | SMITH JACK V (US) | 2003-10-02 | — | — | US | disclosed |
| US-6537823-B1 | Use in determination of adulterants in illicit drug screening samples as a means of detecting false negative results | SCITECK DIAGNOSTICS, INC. | 2003-03-25 | — | — | US | disclosed |
| US-20030045003-A1 | Method for detection of the adulterant urine luckTM in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2003-03-06 | — | — | US | disclosed |
| US-20030027350-A1 | Method for detection of bromine in urine using liquid chemistry, dry chemistry test pads, and lateral flow | SMITH JACK V (US) | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | SQLE, COASY, DHPS | NPC1 3709/4885MAPK13 4250/4885MAPK12 3592/4885 |
| US-20040097728-A1 | Method for producing anellated tetrahydro-{1h}-triazoles | CBR1, CBR3, QSOX1 | NPC1 4155/4885MAPK13 4368/4885MAPK12 4588/4885 |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | SQLE, COASY, DHPS | NPC1 3709/4885MAPK13 4250/4885MAPK12 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.