Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726472 | 0.84 | GABRA1 (0.41) | RPS6KA3PTGS2CYP19A1 | |
| SCHEMBL7044027 | 0.83 | PTGS2 (0.41) | RPS6KA3ALDH1A1HPGDALOX5APFEN1 | |
| SCHEMBL6718301 | 0.82 | TGFBR1 (0.45) | RPS6KA3ALOX5APFEN1PTGS2 | |
| SCHEMBL6725948 | 0.81 | RPS6KA3 (0.46) | RPS6KA3ALOX5APFEN1PTGS2 | |
| SCHEMBL6723317 | 0.81 | RPS6KA3 (0.59) | RPS6KA3ALOX5APFEN1PTGS2 | |
| SCHEMBL6731479 | 0.80 | RPS6KA3 (0.41) | RPS6KA3HPGDPTGS2CYP19A1KDM4E | |
| SCHEMBL6720109 | 0.80 | SCN9A (0.39) | ALDH1A1HPGDALOX5APFEN1KDM4E | |
| SCHEMBL6729507 | 0.80 | RPS6KA3 (0.51) | RPS6KA3ALOX5APFEN1PTGS2 | |
| SCHEMBL6725964 | 0.80 | RPS6KA3 (0.45) | RPS6KA3ALOX5APFEN1PTGS2 | |
| SCHEMBL6722648 | 0.80 | RPS6KA3 (0.45) | RPS6KA3ALOX5APFEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, PTGES2, FPR1 | RPS6KA3 972/4885ALDH1A1 298/4885HPGD 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.